The Pan American Health Organization (PAHO) has introduced HEARTS 2.0, an updated clinical pathway for the Americas that builds on the original model for hypertension control while expanding recommendations to integrate cardio‑renal‑metabolic conditions. This pathway provides a standardized, evidence‑based approach for managing hypertension and cardiovascular risk in primary health care, covering diagnosis, treatment, and follow‑up within a single framework.
The first version of the pathway had already been adopted as the national standard in 29 countries, with adaptations to local contexts. HEARTS 2.0 enhances this model, serving as the foundation for future updates and helping optimize population health outcomes. It is part of PAHO’s broader Better Care for NCDs initiative, which promotes prevention and control of noncommunicable diseases through accessible, coordinated, and community‑centered primary care.
HEARTS 2.0 is designed as a living instrument that evolves with new evidence. Developed through a three‑phase process, it incorporates 45 interventions covering hypertension, cardiovascular disease, diabetes, and chronic kidney disease. The pathway draws on leading global clinical practice guidelines and applies a consensus methodology to ensure rigor and practicality.
The new version emphasizes accurate diagnosis, early screening, standardized treatment protocols, essential medicines, and clear guidance for follow‑up and preventive strategies. By integrating these elements, HEARTS 2.0 advances the evolution of cardiovascular care in the Americas toward a more comprehensive and integrated approach to hypertension and cardio‑renal‑metabolic prevention.







