The Global Fund to Fight AIDS, Tuberculosis and Malaria announced private sector pledges totaling more than US$1 billion this past week, marking a significant milestone in its Eighth Replenishment. These contributions highlight the essential role of private sector partners in advancing global health innovation, equity, and resilience. The pledges, unveiled at the Global Fund’s Eighth Replenishment reception, will support the organization’s mission to fight deadly infectious diseases and strengthen health systems worldwide.
Notable contributions include the Gates Foundation’s US$912 million pledge at the 2025 Goalkeepers event, bringing its total support since 2002 to nearly US$5 billion. The foundation’s commitment reinforces its position as the Global Fund’s largest private donor and underscores its ongoing efforts to end AIDS, tuberculosis (TB), and malaria while scaling innovations to reduce child mortality. (RED) pledged US$75 million, continuing a partnership of nearly two decades, while the Children’s Investment Fund Foundation (CIFF) committed US$50 million to accelerate innovative TB diagnostics, marking its first investment in TB. Goodbye Malaria renewed its support with a US$5.5 million pledge to fight malaria in Southern Africa, and the Johnson & Johnson Foundation pledged US$5 million to expand professionalized community health workers across Africa.
The 2025 Results Report from the Global Fund emphasizes the transformative power of collaboration, highlighting that over the past two decades, the partnership has saved 70 million lives. Executive Director Peter Sands noted that the Replenishment represents more than funding—it is a catalyst for redefining global health leadership by leveraging financial resources, innovation, and influence to achieve sustainable progress. Bill Gates added that while past efforts have saved countless lives, more work is needed to ensure future generations grow up free from preventable diseases.
These private sector pledges will contribute to the Global Fund’s next three-year grant cycle. A fully funded replenishment has the potential to save up to 23 million more lives, strengthen health and community systems, and reinforce global pandemic preparedness. The contributions also bring innovation and reach that can transform approaches to combating AIDS, TB, and malaria, demonstrating the impact of coordinated public and private action.
Leaders from contributing organizations emphasized the importance of these commitments. CIFF’s Chris Hohn highlighted the moral urgency of addressing TB and the scalable impact of innovative diagnostics. (RED)’s Jennifer Lotito reaffirmed the need for sustained support in the fight against AIDS. Johnson & Johnson’s Vanessa Broadhurst noted that expanding community health workers can save millions of lives and strengthen locally-led health systems, while Goodbye Malaria’s Sherwin Charles emphasized the role of collective action in building healthier, more resilient communities in Southern Africa.
