As the world marks World AIDS Day 2025 under the theme “Overcoming disruption, transforming the AIDS response,” the global community faces both opportunities and challenges in ending AIDS as a public health threat. Despite decades of progress, gains are being threatened by tightening financing, conflict, climate shocks, and growing inequalities. Persistent issues such as underinvestment in prevention, overreliance on external aid, fragmented approaches, and stigma continue to hinder progress. Even before recent disruptions, no country was on track to meet the #Triple10Targets by 2025, which aim to eliminate stigma, discrimination, gender-based violence, and punitive laws that restrict access to HIV prevention, treatment, and care. New infections are rising in several regions, particularly among key populations and their partners.
The HIV response has always been defined by overcoming obstacles. Communities, health workers, and people living with HIV have challenged stigma and transformed approaches to health and rights. This spirit of equity, inclusion, and community leadership remains central today. Countries like Namibia and Angola have advanced rights-affirming reforms to strengthen the enabling environment for HIV services. In Kazakhstan, government support for community-led organizations is expanding prevention and legal support services, while in Pakistan, digital platforms co-created with key populations are connecting thousands to confidential information, self-testing, and care.
Scientific innovation continues to drive the fight against HIV. Long-acting HIV prevention tools and partnerships to expand access, such as the agreement to make generic lenacapavir available at $40 per year in 120 low- and middle-income countries by 2027, demonstrate the power of science and solidarity. Maximizing the impact of these innovations requires removing structural barriers, strengthening health systems, and ensuring community organizations, especially key population networks, play a central role in implementation.
For over three decades, the United Nations Development Programme (UNDP) has addressed the development dimensions that influence the epidemic, including promoting inclusive governance, tackling inequalities, supporting key populations, and building resilient health systems. Working alongside UNAIDS, WHO, governments, the Global Fund, civil society, and communities, UNDP remains committed to ending AIDS as a public health threat. This World AIDS Day reaffirms that every life matters, every community has a role, and together, disruption can be transformed into action and hope into health for all.







