Zambia has officially launched the R21/Matrix-M malaria vaccine under its Expanded Programme on Immunization (EPI), marking a major step in its fight against malaria. The rollout, led by the Ministry of Health, will initially target over 500,000 children aged 6–8 months in 83 districts, with the second phase planned for 2026. The country becomes the 24th in the world to introduce the malaria vaccine, with 532,200 doses already received through UNICEF’s support and funding from Gavi, the Vaccine Alliance.
Malaria remains a leading cause of illness and death in Zambia, especially among children under five. In 2023, the country recorded an incidence rate of 523 cases per 1,000 children in this age group. The new vaccine, administered in four doses between 6 and 23 months of age, is expected to significantly reduce the disease burden and improve child health outcomes.
Health Minister Elijah Muchima emphasized that while the vaccine is a breakthrough, it complements ongoing malaria control efforts such as bed net distribution, indoor spraying, and preventive therapies, in line with the National Malaria Elimination Strategic Plan and WHO recommendations.
UNICEF, WHO, and Gavi have been key partners in the initiative, supporting vaccine procurement, cold chain logistics, capacity building, and community outreach. UNICEF Representative Dr. Saja Farooq Abdullah highlighted the vaccine’s potential to save lives and build a healthier, more resilient future for Zambia’s children, while WHO Representative Dr. Peter Clement Lasuba called the launch a landmark moment in Zambia’s commitment to innovation and health equity.
The rollout reflects strong collaboration among government agencies and development partners, including the World Bank, USAID/PMI, the Global Fund, PATH, and CHAZ. According to Gavi’s Senior Country Manager, Jamilya Sherova, Zambia’s participation continues the rapid regional expansion of malaria vaccine programs across Africa. Delivered free of charge through clinics and outreach programs, the vaccine complements Zambia’s broader malaria elimination strategies focused on diagnosis, treatment, and community-based prevention.
