The World Health Organization (WHO) has stated that there is currently no conclusive scientific evidence linking the use of acetaminophen (paracetamol) during pregnancy with autism. Globally, nearly 62 million people, or approximately 1 in 127, are diagnosed with autism spectrum disorder (ASD), a complex group of neurodevelopmental conditions. While awareness and diagnosis have improved, the exact causes of autism remain unclear and are believed to involve multiple factors.
Over the past decade, extensive research—including large-scale studies—has investigated potential associations between acetaminophen use during pregnancy and autism, but no consistent link has been identified. WHO advises that women should continue following the guidance of their healthcare providers regarding medicine use during pregnancy, especially in the first trimester, to ensure safety for both mother and child.
WHO also underscores that childhood vaccines do not cause autism. Large, high-quality studies worldwide have consistently disproven any connection, and earlier flawed studies suggesting a link have been discredited. Since 1999, independent experts advising WHO have repeatedly affirmed that vaccines, including those containing thiomersal or aluminum, are safe and do not lead to autism or other developmental disorders.
Childhood immunization schedules, developed based on rigorous evidence and expert input, have been widely adopted and are essential for safeguarding the health of children, adolescents, and adults. Over the past 50 years, these schedules have helped save at least 154 million lives, protecting against 30 infectious diseases. WHO’s Strategic Advisory Group of Experts on Immunization (SAGE) ensures that vaccine recommendations are evidence-based, delivered at the most effective times, and designed to offer optimal protection against serious diseases.
Disruptions or delays in immunization schedules can significantly increase the risk of infection for both children and the broader community, particularly affecting infants too young to be vaccinated and individuals with weakened immune systems. WHO emphasizes that protecting community health depends on adherence to evidence-based vaccination programs.
Autism and other neurodevelopmental disorders are recognized as priority mental health conditions at the 4th UN High-Level Meeting on NCDs and mental health. WHO is committed to advancing understanding of autism, supporting evidence-based care, and promoting inclusive practices for autistic individuals and their families. The organization collaborates with autistic-led groups and other stakeholders to ensure that people with autism are treated with dignity, free from stigma, and receive appropriate support informed by scientific evidence.
